They were ware of it, and {c} fled unto Lystra and Derbe, cities of Lycaonia, and unto the region that lieth round about:

(c) It is sometimes proper to flee dangers, at the appropriate times.

People's New Testament

14:6 Fled to Lystra and Derbe. These were Lycaonian cities, not far from Iconium. Neither now exists, but the ruins of Lystra, and those of Derbe it is thought, are identical. The first is called by a name meaning The Thousand and One Churches, on account of the ruins of so many sacred edifices. Lystra is named frequently in early church history as a center of Christian influence.

Jamieson-Fausset-Brown Bible Commentary

6. unto Lystra and Derbe-the one some twenty miles to the south, the other some sixty miles to the east of Iconium, somewhere near the bases of what are called the Black Mountains and the roots of Mount Taurus; but their exact position has not yet been discovered.

Matthew Henry's Concise Commentary

14:1-7 The apostles spake so plainly, with such evidence and proof of the Spirit, and with such power; so warmly, and with such concern for the souls of men; that those who heard them could not but say, God was with them of a truth. Yet the success was not to be reckoned to the manner of their preaching, but to the Spirit of God who used that means. Perseverance in doing good, amidst dangers and hardships, is a blessed evidence of grace. Wherever God's servants are driven, they should seek to declare the truth. When they went on in Christ's name and strength, he failed not to give testimony to the word of his grace. He has assured us it is the word of God, and that we may venture our souls upon it. The Gentiles and Jews were at enmity with one another, yet united against Christians. If the church's enemies join to destroy it, shall not its friends unite for its preservation? God has a shelter for his people in a storm; he is, and will be their Hiding-place. In times of persecution, believers may see cause to quit a spot, though they do not quit their Master's work.