And it came to pass, when Moses held up his hand, that Israel prevailed: and when he let {g} down his hand, Amalek prevailed.

(g) So that we see how dangerous a thing it is to cease in prayer.

Wesley's Notes

17:11 And when Moses held vp his hand in prayer (so the Chaldee explains it) Israel prevailed, but when he let down his hand from prayer, Amalek prevailed - To convince Israel that the hand of Moses (with whom they had just now been chiding) contributed more to their safety than their own hands; the success rises and falls, as Moses lifts up or lets down his hand. The church's cause is ordinarily more or less successful, according as the church's friends are more or less fervent in prayer.

Matthew Henry's Concise Commentary

17:8-16 Israel engaged with Amalek in their own necessary defence. God makes his people able, and calls them to various services for the good of his church. Joshua fights, Moses prays, both minister to Israel. The rod was held up, as the banner to encourage the soldiers. Also to God, by way of appeal to him. Moses was tired. The strongest arm will fail with being long held out; it is God only whose hand is stretched out still. We do not find that Joshua's hands were heavy in fighting, but Moses' hands were heavy in praying; the more spiritual any service is, the more apt we are to fail and flag in it. To convince Israel that the hand of Moses, whom they had been chiding, did more for their safety than their own hands, his rod than their sword, the success rises and falls as Moses lifts up or lets down his hands. The church's cause is more or less successful, as her friends are more or less strong in faith, and fervent in prayer. Moses, the man of God, is glad of help. We should not be shy, either of asking help from others, or of giving help to others. The hands of Moses being thus stayed, were steady till the going down of the sun. It was great encouragement to the people to see Joshua before them in the field of battle, and Moses above them on the hill. Christ is both to us; our Joshua, the Captain of our salvation, who fights our battles, and our Moses, who ever lives, making intercession above, that our faith fail not. Weapons formed against God's Israel cannot prosper long, and shall be broken at last. Moses must write what had been done, what Amalek had done against Israel; write their bitter hatred; write their cruel attempts; let them never be forgotten, nor what God had done for Israel in saving them from Amalek. Write what should be done; that in process of time Amalek should be totally ruined and rooted out. Amalek's destruction was typical of the destruction of all the enemies of Christ and his kingdom.