But when it pleased God, who {l} separated me from my mother's womb, and called me by his grace,

(l) He speaks of God's everlasting predestination, by which he appointed him to be an apostle, of which he makes three distinctions: the everlasting council of God, his appointing from his mother's womb, and his calling. And we see that there is no mention at all of foreseen works.

People's New Testament

1:15 But when it pleased God, etc. The language that follows implies that, like Moses, John the Baptist (Lu 1:15-17), Isaiah (Isa 49:1), and Jeremiah (Jer 1:5), Paul was destined to his work from birth.

Wesley's Notes

1:15 But when it pleased God - He ascribes nothing to his own merits, endeavours, or sincerity. Who separated me from my mother's womb - Set me apart for an apostle, as he did Jeremiah for a prophet. Jer 1:5. Such an unconditional predestination as this may consist, both with God's justice and mercy. And called me by his grace - By his free and almighty love, to be both a Christian and an apostle.

Jamieson-Fausset-Brown Bible Commentary

15. separated-"set me apart": in the purposes of His electing love (compare Ac 9:15; 22:14), in order to show in me His "pleasure," which is the farthest point that any can reach in inquiring the causes of his salvation. The actual "separating" or "setting apart" to the work marked out for him, is mentioned in Ac 13:2; Ro 1:1. There is an allusion, perhaps, in the way of contrast, to the derivation of Pharisee from Hebrew, "pharash," "separated." I was once a so-called Pharisee or Separatist, but God had separated me to something far better.

from . womb-Thus merit in me was out of the question, in assigning causes for His call from Ac 9:11. Grace is the sole cause (Ps 22:9; 71:6; Isa 49:1, 5; Jer 1:5; Lu 1:15).

called me-on the way to Damascus (Ac 9:3-8).

Matthew Henry's Concise Commentary

1:15-24 St. Paul was wonderfully brought to the knowledge and faith of Christ. All who are savingly converted, are called by the grace of God; their conversion is wrought by his power and grace working in them. It will but little avail us to have Christ revealed to us, if he is not also revealed in us. He instantly prepared to obey, without hesitating as to his worldly interest, credit, ease, or life itself. And what matter of thanksgiving and joy is it to the churches of Christ, when they hear of such instances to the praise of the glory of his grace, whether they have ever seen them or not! They glorify God for his power and mercy in saving such persons, and for all the service to his people and cause that is done, and may be further expected from them.