Therefore God give thee of the dew of heaven, and the fatness of the earth, and plenty of corn and wine:

Wesley's Notes

27:27-31 He kissed him; in token of particular affection to him. Those that are blessed of God are kissed with the kisses of his mouth, and they do by love and loyalty kiss the son, Psa 2:12.
2. He praised him. Upon occasion of the sweet smell of his garments he said, See the smell of my son is as the smell of a field which the Lord hath blessed - That is, like that of the most fragrant flowers and spices. Three things Jacob is here blessed with, Plenty, Ge 27:28. Heaven and earth concurring to make him rich. Power, Ge 27:29. Particularly dominion over his brethren, viz. Esau and his posterity. Prevalency with God, and a great interest in heaven, Cursed be every one that curseth thee - Let God be a friend to all thy friends, and an enemy to all thine enemies. Now, certainly more is comprised in this blessing than appears at first; it must amount to an entail of the promise of the Messiah: that was in the patriarchal dialect the blessing; something spiritual doubtless is included in it. First, That from him should come the Messiah, that should have a sovereign dominion on earth. See Num 24:19. Out of Jacob shall come he that shall have dominion, the star and scepter, Nu 24:17. Jacob's dominion over Esau was to be only typical of this, Gen 49:10. Secondly, That from him should come the church that should be particularly owned and favoured by Heaven. It was part of the blessing of Abraham when he was first called to be the father of the faithful, Gen 12:3. I will bless them that bless thee; therefore when Isaac afterwards confirmed the blessing to Jacob, he called it the blessing of Abraham, Gen 28:4.

Jamieson-Fausset-Brown Bible Commentary

Ge 27:28-46. The Blessing.

28. God give thee of the dew of heaven-To an Oriental mind, this phraseology implied the highest flow of prosperity. The copious fall of dew is indispensable to the fruitfulness of lands, which would be otherwise arid and sterile through the violent heat; and it abounds most in hilly regions, such as Canaan, hence called the "fat land" (Ne 9:25, 35).

plenty of corn and wine-Palestine was famous for vineyards, and it produced varieties of corn, namely, wheat, barley, oats, and rye.

Matthew Henry's Concise Commentary

27:18-29 Jacob, with some difficulty, gained his point, and got the blessing. This blessing is in very general terms. No mention is made of the distinguishing mercies in the covenant with Abraham. This might be owing to Isaac having Esau in his mind, though it was Jacob who was before him. He could not be ignorant how Esau had despised the best things. Moreover, his attachment to Esau, so as to disregard the mind of God, must have greatly weakened his own faith in these things. It might therefore be expected, that leanness would attend his blessing, agreeing with the state of his mind.