Thou shalt not take {a} thee a wife, neither shalt thou have sons nor daughters in this place.

(a) Meaning that the affliction would be so horrible in Jerusalem that a wife and children would only increase his sorrow.

Jamieson-Fausset-Brown Bible Commentary

2. in this place-in Judea. The direction to remain single was (whether literally obeyed, or only in prophetic vision) to symbolize the coming calamities of the Jews (Eze 24:15-27) as so severe that the single state would be then (contrary to the ordinary course of things) preferable to the married (compare 1Co 7:8, 26, 29; Mt 24:19; Lu 23:29).

Matthew Henry's Concise Commentary

16:1-9 The prophet must conduct himself as one who expected to see his country ruined very shortly. In the prospect of sad times, he is to abstain from marriage, mourning for the dead, and pleasure. Those who would convince others of the truths of God, must make it appear by their self-denial, that they believe it themselves. Peace, inward and outward, family and public, is wholly the work of God, and from his loving-kindness and mercy. When He takes his peace from any people, distress must follow. There may be times when it is proper to avoid things otherwise our duty; and we should always sit loose to the pleasures and concerns of this life.