Against ... - i. e., relating to, concerning. So Jeremiah 48:1; Jeremiah 49:1; see the note at Jeremiah 46:13.

Pharaoh-necho - See 2 Kings 23:29 note.

In - (at) Carchemish - (The Gargamis of the inscriptions, now Jerabis, on the Euphrates, about 16 miles south of Birejik.)

Pharaoh-necho - This was the person who defeated the army of Josiah, in which engagement Josiah received a mortal wound, of which he died, greatly regretted, soon after at Megiddo. After this victory, he defeated the Babylonians, and took Carchemish; and, having fortified it, returned to his own country. Nabopolassar sent his son Nebuchadnezzar with an army against him, defeated him with immense slaughter near the river Euphrates, retook Carchemish, and subdued all the revolted provinces, according to the following prophecies.

Against Egypt,.... This is the title of the first prophecy against Egypt; which is the first mentioned, because first accomplished; and because the Jews placed great confidence in and much relied on the Egyptians for help:

against the army of Pharaohnecho king of Egypt; who is by Herodotus (q) called Necos; he was the son and successor of Psammitichus, and was succeeded by his son Psammis; and he by Apries, the same with Pharaohhophra, Jeremiah 44:30; the Targum calls this king Pharaoh the lame:

which was by the river Euphrates in Carchemish; of which place See Gill on Isaiah 10:9; this being in the land of the king of Assyria, as appears from the same place. Pharaohnecho, in Josiah's time, came up against him, in order to take it from him; but whether he did or no is not certain; see 2 Kings 23:29; however, he appeared at the same place a second time, against the king of Babylon, into whose hands it was now very probably fallen, with the whole Assyrian monarchy; and here, in this second battle, his army was routed, as follows:

which Nebuchadnezzar king of Babylon smote in the fourth year of Jehoiakim the son of Josiah king of Judah; when he took away from the king of Egypt all that belonged to him between the Nile and Euphrates, so that he came no more out of his land, 2 Kings 24:7. Kimchi and Abarbinel think there was but one expedition of Pharaohnecho; and that the siege of Carchemish continued to the fourth year of Jehoiakim; when he met with an entire overthrow from the king of Babylon, which God suffered as a judgment on him for killing Josiah. This, according to Bishop Usher, was in the year of the world 3397, and before Christ 607; and, according to the Universal History, in the year of the world 3396, and before Christ 608.

(q) L. 2. sive Euterpe, c. 158.

Against Egypt, against the army of {b} Pharaohnecho king of Egypt, who was by the river Euphrates in Carchemish, whom Nebuchadnezzar king of Babylon smote in the fourth year of Jehoiakim the son of Josiah king of Judah.

(b) Read 2Ki 23:29,24:7, 2Ch 35:20.

2. Inscription of the first prophecy.

Pharaoh-necho-He, when going against Carchemish (Cercusium, near the Euphrates), encountered Josiah, king of Judah (the ally of Assyria), at Megiddo, and slew him there (2Ki 23:29; 2Ch 35:20-24); but he was four years subsequently overcome at Carchemish, by Nebuchadnezzar, as is foretold here; and lost all the territory which had been subject to the Pharaohs west of the Euphrates, and between it and the Nile. The prediction would mitigate the Jews' grief for Josiah, and show his death was not to be unavenged (2Ki 24:7). He is famed as having fitted out a fleet of discovery from the Red Sea, which doubled the Cape of Good Hope and returned to Egypt by the Mediterranean.

46:1-12 The whole word of God is against those who obey not the gospel of Christ; but it is for those, even of the Gentiles, who turn to Him. The prophecy begins with Egypt. Let them strengthen themselves with all the art and interest they have, yet it shall be all in vain. The wounds God inflicts on his enemies, cannot be healed by medicines. Power and prosperity soon pass from one to another in this changing world.