His sons come to honour, and he knoweth it not; and they are brought low, but he perceiveth it not of them.

Wesley's Notes

14:21 Knoweth not - Either is ignorant of all such events: or, is not concerned or affected with them. A dead or dying man minds not these things.

Jamieson-Fausset-Brown Bible Commentary

21. One striking trait is selected from the sad picture of the severance of the dead from all that passes in the world (Ec 9:5), namely, the utter separation of parents and children.

Matthew Henry's Concise Commentary

14:16-22 Job's faith and hope spake, and grace appeared to revive; but depravity again prevailed. He represents God as carrying matters to extremity against him. The Lord must prevail against all who contend with him. God may send disease and pain, we may lose all comfort in those near and dear to us, every hope of earthly happiness may be destroyed, but God will receive the believer into realms of eternal happiness. But what a change awaits the prosperous unbeliever! How will he answer when God shall call him to his tribunal? The Lord is yet upon a mercy-seat, ready to be gracious. Oh that sinners would be wise, that they would consider their latter end! While man's flesh is upon him, that is, the body he is so loth to lay down, it shall have pain; and while his soul is within him, that is, the spirit he is so loth to resign, it shall mourn. Dying work is hard work; dying pangs often are sore pangs. It is folly for men to defer repentance to a death-bed, and to have that to do which is the one thing needful, when unfit to do anything.