And this is the Father's will which hath sent me, that of all which he hath given me I should lose nothing, but should raise it up again at the last day.

People's New Testament

6:39,40 This is the Father's will. The Father's will is that every one who sees the Son and believes upon him, thus coming to, following and abiding in him, shall have eternal life, and that in the resurrection day Christ shall raise him from the grave. These verses show, (1) That there is not any secret decree of election. The will of the Father applies to every one who believes upon the Son. (2) The condition of eternal life is a faith that leads to and appropriates Christ; that makes him the Lord of the soul. (3) Christ hath brought to light immortality. He is the resurrection and the life (Joh 11:25).

Wesley's Notes

6:39 Of all which he hath already given me - See Joh 17:6,12. If they endure to the end. But Judas did not.

Jamieson-Fausset-Brown Bible Commentary

39. And this-in the first place.

is the will of Him that sent me, that of all-everything.

which He hath given Me-(taking up the identical words of Joh 6:37).

I should lose nothing, but should raise it up at the last day-The meaning is not, of course, that He is charged to keep the objects entrusted to Him as He received them, so as they should merely suffer nothing in His hands. For as they were just "perishing" sinners of Adam's family, to let "nothing" of such "be lost," but "raise them up at the last day," must involve, first, giving His flesh for them (Joh 6:51), that they "might not perish, but have everlasting life"; and then, after "keeping them from falling," raising their sleeping dust in incorruption and glory, and presenting them, body and soul, perfect and entire, wanting nothing, to Him who gave them to Him, saying, "Behold I and the children which God hath given Me." So much for the first will of Him that sent Him, the divine side of man's salvation, whose every stage and movement is inscrutable to us, but infallibly certain.

Matthew Henry's Concise Commentary

6:36-46 The discovery of their guilt, danger, and remedy, by the teaching of the Holy Spirit, makes men willing and glad to come, and to give up every thing which hinders applying to him for salvation. The Father's will is, that not one of those who were given to the Son, should be rejected or lost by him. No one will come, till Divine grace has subdued, and in part changed his heart; therefore no one who comes will ever be cast out. The gospel finds none willing to be saved in the humbling, holy manner, made known therein; but God draws with his word and the Holy Ghost; and man's duty is to hear and learn; that is to say, to receive the grace offered, and consent to the promise. None had seen the Father but his beloved Son; and the Jews must expect to be taught by his inward power upon their minds, and by his word, and the ministers whom he sent among them.