The kings of the earth set themselves, and the rulers take counsel together, against the LORD, and against his anointed, saying,

Wesley's Notes

2:2 The kings - Herod, and Pilate and others with or after them. Earth - So called in way of contempt and to shew their madness in opposing the God of heaven. Set - The word denotes the combination of their counsels and forces. Anointed - Against the king whom God hath chosen and exalted.

Jamieson-Fausset-Brown Bible Commentary

2. The kings and rulers lead on their subjects.

set themselves-take a stand.

take counsel-literally, "sit together," denoting their deliberation.

anointed-Hebrew, "Messiah"; Greek, "Christ" (Joh 1:41). Anointing, as an emblem of the gifts of the Holy Spirit, was conferred on prophets (Isa 6:1); priests (Ex 30:30); and kings (1Sa 10:1; 16:13; 1Ki 1:39). Hence this title well suited Him who holds all these offices, and was generally used by the Jews before His coming, to denote Him (Da 9:26). While the prophet has in view men's opposition generally, he here depicts it in its culminating aspect as seen in the events of Christ's great trial. Pilate and Herod, and the rulers of the Jews (Mt 27:1; Lu 23:1-25), with the furious mob, are vividly portrayed.

Matthew Henry's Concise Commentary

2:1-6 We are here told who would appear as adversaries to Christ. As this world is the kingdom of Satan, unconverted men, of every rank, party, and character, are stirred up by him to oppose the cause of God. But the rulers of the earth generally have been most active. The truths and precepts of Christianity are against ambitious projects and worldly lusts. We are told what they aim at in this opposition. They would break asunder the bands of conscience, and the cords of God's commandments; they will not receive, but cast them away as far as they can. These enemies can show no good cause for opposing so just and holy a government, which, if received by all, would bring a heaven upon earth. They can hope for no success in so opposing so powerful a kingdom. The Lord Jesus has all power both in heaven and in earth, and is Head over all things to the church, notwithstanding the restless endeavours of his enemies. Christ's throne is set up in his church, that is, in the hearts of all believers.