And he said, Behold, I will make thee know what shall be in the last {e} end of the indignation: for at the time appointed the end shall be.

(e) Meaning that great rage which Antiochus would show against the Church.

Wesley's Notes

8:19 The indignation - God will raise up Antiochus to execute his wrath against the Jews for their sins, yet there shall be an end of that indignation.

Scofield Reference Notes

[1] end

Two "ends" are in view here:

(1) historically, the end of the third, or Grecian empire of Alexander out of one of the divisions of which the little horn of verse 9 (Antiochus) arose;

(2) prophetically, the end of the times of the Gentiles Lk 21:24 Rev 16:14 when the "little horn" of Dan 7:8,24-26 the Beast, will arise--Daniel's final time of the end. See Scofield Note: "Dan 12:4".

Jamieson-Fausset-Brown Bible Commentary

19. the last end of the indignation-God's displeasure against the Jews for their sins. For their comfort they are told, the calamities about to come are not to be for ever. The "time" is limited (Da 9:27; 11:27, 35, 36; 12:7; Hab 2:3).

Matthew Henry's Concise Commentary

8:15-27 The eternal Son of God stood before the prophet in the appearance of a man, and directed the angel Gabriel to explain the vision. Daniel's fainting and astonishment at the prospect of evils he saw coming on his people and the church, confirm the opinion that long-continued calamities were foretold. The vision being ended, a charge was given to Daniel to keep it private for the present. He kept it to himself, and went on to do the duty of his place. As long as we live in this world we must have something to do in it; and even those whom God has most honoured, must not think themselves above their business. Nor must the pleasure of communion with God take us from the duties of our callings, but we must in them abide with God. All who are intrusted with public business must discharge their trust uprightly; and, amidst all doubts and discouragements, they may, if true believers, look forward to a happy issue. Thus should we endeavour to compose our minds for attending to the duties to which each is appointed, in the church and in the world.