The same shall drink of the wine of the wrath of God, which is poured out without mixture into the cup of his indignation; and he shall be tormented with fire and brimstone in the presence of the holy angels, and in the presence of the Lamb:

People's New Testament

14:10 The same shall drink of the wine of the wrath of God. Those who received the mark of the beast, worshiped the beast, drank the wine of Babylon, shall drink the wine of God's wrath. His judgments shall be poured out on them. He shall be tormented with fire and brimstone. These are symbols, just as wine and cup are symbols. The meaning is that they shall suffer bitter anguish.

Wesley's Notes

14:10 He shall drink - With Babylon, Rev 16:19. And shall be tormented - With the beast, Rev 20:10. In all the scripture there is not another so terrible threatening as this. And God by this greater fear arms his servants against the fear of the beast. The wrath of God, which is poured unmixed - Without any mixture of mercy; without hope. Into the cup of his indignation - And is no real anger implied in all this? O what will not even wise men assert, to serve an hypothesis!

Scofield Reference Notes

Margin angels

See Scofield Note: "Heb 1:4".

Jamieson-Fausset-Brown Bible Commentary

10. The same-Greek, "he also," as the just and inevitable retribution.

wine of . wrath of God-(Ps 75:8).

without mixture-whereas wine was so commonly mixed with water that to mix wine is used in Greek for to pour out wine; this wine of God's wrath is undiluted; there is no drop of water to cool its heat. Naught of grace or hope is blended with it. This terrible threat may well raise us above the fear of man's threats. This unmixed cup is already mingled and prepared for Satan and the beast's followers.

indignation-Greek, "orges," "abiding wrath," But the Greek for "wrath" above (Greek, "thumou") is boiling indignation, from (Greek, "thuo") a root meaning "to boil"; this is temporary ebullition of anger; that is lasting [Ammonius], and accompanied with a purpose of vengeance [Origen on Psalm 2:5].

tormented . in the presence of . angels-(Ps 49:14; 58:10; 139:21; Isa 66:24). God's enemies are regarded by the saints as their enemies, and when the day of probation is past, their mind shall be so entirely one with God's, that they shall rejoice in witnessing visibly the judicial vindication of God's righteousness in sinners' punishment.

Matthew Henry's Concise Commentary

14:6-13 The progress of the Reformation appears to be here set forth. The four proclamations are plain in their meaning; that all Christians may be encouraged, in the time of trial, to be faithful to their Lord. The gospel is the great means whereby men are brought to fear God, and to give glory to him. The preaching of the everlasting gospel shakes the foundations of antichrist in the world, and hastens its downfal. If any persist in being subject to the beast, and in promoting his cause, they must expect to be for ever miserable in soul and body. The believer is to venture or suffer any thing in obeying the commandments of God, and professing the faith of Jesus. May God bestow this patience upon us. Observe the description of those that are and shall be blessed: such as die in the Lord; die in the cause of Christ, in a state of union with Christ; such as are found in Christ when death comes. They rest from all sin, temptation, sorrow, and persecution; for there the wicked cease from troubling, there the weary are at rest. Their works follow them: do not go before as their title, or purchase, but follow them as proofs of their having lived and died in the Lord: the remembrance of them will be pleasant, and the reward far above all their services and sufferings. This is made sure by the testimony of the Spirit, witnessing with their spirits, and the written word.