Neither shall he regard the {u} God of his fathers, nor the desire {x} of women, nor regard any god: for he shall magnify himself above all.

(u) The Romans will observe no certain form of religion as other nations, but will change their gods at their pleasures, indeed, they will condemn them and prefer themselves to their gods.

(x) Signifying that they would be without all humanity: for the love of women is taken for singular or great love, as 2Sa 1:26.

Jamieson-Fausset-Brown Bible Commentary

37. Neither . regard . the desire of women-(Compare Eze 24:16, 18). The wife, as the desire of man's eyes, is the symbol of the tenderest relations (2Sa 1:26). Antiochus would set at naught even their entreaties that he should cease from his attack on Jehovah's worship [Polanus]. Maurer refers it to Antiochus' attack on the temple of the Syrian Venus, worshipped by women (1 Maccabees 6:1, &c.; 2 Maccabees 1:13). Newton refers it to Rome's "forbidding to marry." Elliott rightly makes the antitypical reference be to Messiah. Jewish women desired to be mothers with a view to Him, the promised seed of the woman (Ge 30:23; Lu 1:25, 28).

nor regard any god-(2Th 2:4).

Matthew Henry's Concise Commentary

11:31-45 The remainder of this prophecy is very difficult, and commentators differ much respecting it. From Antiochus the account seems to pass to antichrist. Reference seems to be made to the Roman empire, the fourth monarchy, in its pagan, early Christian, and papal states. The end of the Lord's anger against his people approaches, as well as the end of his patience towards his enemies. If we would escape the ruin of the infidel, the idolater, the superstitious and cruel persecutor, as well as that of the profane, let us make the oracles of God our standard of truth and of duty, the foundation of our hope, and the light of our paths through this dark world, to the glorious inheritance above.